Exploring Fluorinase Substrate Tolerance at C-2 of SAM Wednesday December 4, 2024Tuesday December 3, 2024 by Phillip Lowe Read our paper here
Efficient biotransformations in Cunninghamella elegans and Streptomyces sp. JCM9888 of selectively fluorinated benzoic acids to the corresponding benzamides and benzyl alcohols Thursday October 12, 2023 by Phillip Lowe Read our paper here
3′-O-β-Glucosyl-4′,5′-didehydro-5′-deoxyadenosine Is a Natural Product of the Nucleocidin Producers Streptomyces virens and Streptomyces calvus Tuesday September 26, 2023 by Phillip Lowe Read our paper here
Aryl (β,β′,β″-Trifluoro)-tert-butyl: A Candidate Motif for the Discovery of Bioactives Friday September 8, 2023 by Phillip Lowe Read our paper here
Direct syntheses of stereoisomers of 3-fluoro GABA and b-fluoroamine analogues of the calcium receptor (CaR) agonists, cinacalcet, tecalcet, fendilines and NPS R-467 Friday September 8, 2023Tuesday September 5, 2023 by Phillip Lowe Read our paper here
Future challenges and opportunities with fluorine in drugs? Friday September 8, 2023Friday July 7, 2023 by Phillip Lowe Read our paper here
Lateral dipole moments induced by all-cis-pentafluorocyclohexyl groups cause unanticipated effects in self-assembled monolayers. Monday May 29, 2023 by Phillip Lowe Read our paper here
(3-Methoxy-5-(methoxycarbonyl)isoxazol-4-yl)(4-methoxyphenyl)iodonium 2,2,2-trifluoroacetate. Monday May 29, 2023 by Phillip Lowe Read our paper here
The emergence and properties of selectively fluorinated ‘Janus’ cyclohexanes. Monday May 29, 2023 by Phillip Lowe Read our paper here
Identification of genes essential for fluorination and sulfamylation within the nucleocidin gene clusters of Streptomyces calvus and Streptomyces virens. Friday January 27, 2023Friday January 27, 2023 by Phillip Lowe Read our paper here