2014 Publications

235
Organic chemistry on surfaces: Direct cyclopropanation by dihalocarbene addition to vinyl terminated self-assembled monolayers (SAMs)
Malgorzata Adamkiewicz, David O’Hagan and Georg Hähner

Beilstein J. Org Chem., 2014, 10, 2897–2902.
10.3762/bjoc.10.307


234
Synthesis and anticancer properties of RGD peptides conjugated to nitric oxide releasing functional groups and abiraterone.
Andrew Nortcliffe, Ian N. Fleming, Nigel P. Botting and David O’Hagan

Tetrahedron, 2014, 70, 8343–8347.
10.1016/j.tet.2014.09.004


233
Analysis of CF···FC Interactions on Cyclohexane and Naphthalene Frameworks.
Rodrigo Cormanich, Roberto Rittner, David O’Hagan and Michael Bühl

J. Phys. Chem., 2014, 118, 7901–7910.
10.10.1021/jp504568c


232

Stepwise preparation of all-cis 1,3,4-trifluoro-2-phenylcyclohexane, avoiding a phenonium intermediate.
Alastair J. Durie Tomoya Fujiwara, Nawaf Al-Maharik, Alexandra M. Z. Slawin and David O’Hagan

J. Org. Chem., 2014, 79, 8228–8233.
10.1021/jo501432x


231
Successful fluorine-containing herbicide agrochemicals.
Tomoya Fujiwara and David O’Hagan

J. Fluorine Chem., 2014, 167, 16–29.
10.1016/j.jfluchem.2014.06.014


230
Fluoroacetate biosynthesis from the marine-derived bacterium Streptomyces xinghaiensis NRRL B-24674.
Sheng Huang, Long Ma, Ming Him Tong, Yi Yu,  David O’Hagan and Hai Deng

Org. Biol. Chem., 2014, 12, 4828–4831.
10.1039/C4OB00970C


229
‘A localised tolerance in the substrate specificity of the fluorinase enables ‘last step’ [18F]-fluorination of a RGD peptide under ambient aqueous conditions’.
Stephen Thompson, Qingzhi Zhang, Mayca Onega, Stephen McMahon, Ian Fleming, Sharon Ashworth, James H. Naismith, Jan Passchier, David O’Hagan

Angew. Chemie, Int. Ed., 2014, 53, 8913–8918.
10.1002/anie.201403345


228
Total synthesis of a reported fluorometabolite from Streptomyces sp. TC1 indicates an incorrect assignment.  The isolated compound did not contain fluorine.
Mohammed Salah Ayoup, David B. Cordes, Alexandra M. Z. Slawin and David O’Hagan

J. Nat. Prod., 2014, 77, 1249–1251.
10.1021/np500260z


227
bis-(Trifluoromethyl)methylene addition to vinyl-terminated SAMs: A gas phase C–C bond forming reaction on a surface.
Malgorzata Adamkiewicz, David O’Hagan, and Georg Hähner

Langmuir, 2014, 30, 5422–5428.
10.1021/la5011727


226
The influence of vicinal threo-difluorination on electro-optic and mesogenic properties of propyleneoxy-linked nematic liquid crystals.
Nawaf Al-Maharik, Peer Kirsch, Alexandra M. Z. Slawin, David O’Hagan

Tetrahedron, 2014, 70, 4626–4630.
10.1016/j.tet.2014.05.027


225
Density functional study of interactions between fluorinated cyclohexanes and arenes.
Rodrigo A. Cormanich, Alastair Durie, Ragnar Bjornsson, Roberto Rittner,  David O’Hagan  and Michael Bühl

Helv. Chimica. Acta, 2014, 97, 797–807.
10.1002/hlca.201400049


224
All-cis-1,2,4,5 tetrafluoro-3-phenylcyclohexane, a polar cyclohexane motif.
Alastair J. Durie, Tomoya Fujiwara, Rodrigo Cormanich, Michael Bühl, Alexandra M. Z. Slawin and David O’Hagan

Chem. –Eur. J., 2014, 20, 6259–6263.
10.1002/chem.201400354


223
Molecular recognition of fluorine impacts substrate selectivity in the fluoroacetyl-CoA thioesterase FlK.
Amy Weeks, Neil Keddie, Rudy Wadoux, David  O’Hagan, Michelle Chang

Biochemistry, 2014, 53, 2053–2063.
10.1021/bi4015049


222

Synthesis and biological evaluation of nitric oxide-donating analogues of sulindac for prostate cancer treatment.
Andrew Nortcliffe, Alexander G. Ekstrom, James Black, James A. Ross, Fouad K. Habib, Nigel P. Botting, and David O’Hagan

Bioorg. Med. Chem., 2014, 22, 756–761.
10.1016/j.bmc.2013.12.014


221
Identification of fluorinases from Streptomyces sp. MA37, Norcardia brasiliensis and Actinoplanes sp. N902-109 by gene mining.
Hai Deng, Long Ma, Nouchali Bandaranayaka, Zhiwei Qin, Greg Mann, Kwaku Kyeremeh, Yi Yu, Thomas Shepherd, James H Naismith and David O’Hagan

ChemBioChem, 2014, 15, 364–368.
10.1002/cbic.201300732


220
The difluoromethylene (CF2) group in aliphatic chains: Synthesis and conformational preference of palmitic acids and nonadecane containing CF2 groups.
Yi Wang, Ricardo Callejo, Alexandra M. Z. Slawin, David O’Hagan

Beilstein. J. Org. Chem., 2014, 10, 18–25.
10.3762/bjoc.10.4