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2021 Publications
304
Streptomyces aureorectus DSM 41692 and Streptomyces virens DSM 41465 are producers of the antibiotic nucleocidin and 4′-fluoroadenosine is identified as a co-product
Yawen Chen, Qingzhi Zhang, Xuan Feng, Marta Wojnowska, David O’Hagan
Org. Biomol. Chem., 2021, Advance Article
doi.org/10.1039/D1OB01898A
303
Janus all-cis 2,3,4,5,6-pentafluorocyclohexyl building blocks applied to medicinal chemistry and bioactives discovery chemistry
Joshua L. Clark, Rifahath M. Neyyappadath, Cihang Yu, Alexandra M. Z. Slawin, David B. Cordes, David O’Hagan
Chem. Eur. J., 2021, Accepted Article
doi.org/10.1002/chem.202102819
302
Supramolecular packing of alkyl substituted Janus face all-cis 2,3,4,5,6-pentafluorocyclohexyl motifs
Joshua L. Clark, Alaric Taylor, Ailsa Geddis, Rifahath M. Neyyappadath, Bruno A. Piscelli, Cihang Yu, David B. Cordes, Alexandra M. Z. Slawin, Rodrigo A. Cormanich, Stefan Guldin, David O’Hagan
Chem. Sci., 2021, 11, 450.
doi.org/10.1039/D1SC02130C
301
Effect of fluoroalkyl-substituent in bistolane-based photoluminescence liquid crystals on their physical behaviour
Shigeyuki Yamada, Masato Morita, Yizhou Wang, Qingzhi Zhang, David O’Hagan, Tomohiro Agou, Hiroki Fukumoto, Toshio Kubota, Mitsuo Hara. Tsutomu Konno
Crystals, 2021, Advance Article
doi.org/10.1039/D1SC02130C
300
The contribution of non-classical CHax∙∙∙OC hydrogen bonds to the anomeric effect in fluoro and oxa-methoxycyclohexanes
Bruno A. Piscelli, David O’Hagan, and Rodrigo A. Cormanich
PhysChemChemPhy, 2021, 23, 5845 – 5851.
doi.org/10.1039/D0CP06646J
299
Synthesis, Radiosynthesis, and in vitro Studies on Novel Hypoxia PET Tracers Incorporating [18F]FDR
Manuele Musolino, Ian N. Fleming, Lutz F. Schweiger, Prof. Dr. David O’Hagan, Sergio Dall’Angelo and Matteo Zanda
Eur. J. Org. Chem., 2021, accepted manuscript
doi.org/10.1002/ejoc.202001670
298
Isolation of 5′-O-sulfamyladenosine and related 3′-O-β-glucosylated adenosines from the nucleocidin producer Streptomyces calvus
Xuan Feng, Davide Bello and David O’Hagan
RSC Adv., 2021,11, 5291-5294
doi.org/10.1039/D1RA00235J
2020 Publications
297
A fluoride-responsive genetic circuit enables in vivo biofluorination in engineered Pseudomonas putida
Patricia Calero, Daniel C. Volke, Phillip T. Lowe, Charlotte H. Gotfredsen, David O’Hagan and Pablo I. Nikel
Nature Commun., 2020, 11, 5045
10.1038/s41467-020-18813-x
296
Next generation organofluorine containing blockbuster drugs
Jianlin Han, Attila Márió Remete, Luca S. Dobson, Lorand Kiss, Kunisuke Izawa, Hiroki Moriwaki, Vadim A. Soloshonok and David O’Hagan
J. Fluorine Chem., 2020, 239, 109639
10.1016/j.jfluchem.2020.109639
295
Janus face all-cis 1,2,4,5-tetrakis(trifluoromethyl)- and all-cis 1,2,3,4,5,6-hexakis(trifluoromethyl)- cyclohexanes
Cihang Yu, Agnes Kütt, Gerd-Volker Röschenthaler, Tomas Lebl, David B. Cordes, Alexandra M. Z. Slawin, Michael Bűhl and David O’Hagan
Angewandte Chemie. Int. Ed., 2020, in press.
10.1002/anie.202008662
294
Fluorine induced pseudo-anomeric effects in methoxycyclohexanes through electrostatic 1,3-diaxial interactions
Zeguo Fang, Nawaf Al-Maharik, Peer Kirsch, Matthias Bremer, Alexandra M. Z. Slawin and David O’Hagan
Chem. Eur. J., 2020, in press.
10.1002/chem.202003058
293
Synthesis of organic liquid crystal containing selectively fluorinated cyclopropanes
Zeguo Fang, Nawaf Al-Maharik, Peer Kirsch, Matthias Bremer, Alexandra M. Z. Slawin and David O’Hagan
Beilstein J. Org. Chem., 2020, 16, 674-680.
10.3762/bjoc.16.65
292
Polar organofluorine substituents: Placing fluorines along alkyl chains and around alicyclic rings
David O’Hagan
Chem. Eur. J., 2020, 26, 7981-7997.
10.1002/chem.202000178
291
An engineered E. coli strain for direct in vivo fluorination
Konstantinos Markakis, Phillip T. Lowe, Liam Davison-Gates, David O’Hagan, Susan J.Rosser and Alistair Elfick
ChemBioChem., 2020, 21,1856-1860.
10.1002/cbic.202000051
290
Probing the helical integrity of multivicinal all-syn-fluoro alkanes
Nawaf Al-Maharik, David B. Cordes, Alexandra M. Z. Slawin, Michael Bühl and David O’Hagan
Org. Biomol. Chem., 2020,18, 878-887
10.1039/C9OB02647A
289
A role for fluorine in flavours, fragrances and pheromones
Phillip T. Lowe and David O’Hagan
J. Fluorine Chem., 2020, 109420
10.1016/j.jfluchem.2019.109420
2019 Publications
288
Unexpected α,α’-difluoroethers from Ag(I)F and N-bromosuccinimide reactions of dibenzo[a,e]cyclooctatetraene
Zeguo Fang, Roscoe Z. Gillatt, Alexandra M. Z. Slawin, David B. Cordes, Cameron L. Carpenter-Warren and David O’Hagan
Chem. Commun., 2019, 55, 14295 – 14298
10.1039/C9CC06426E
287
Two 3’-O- β-Glucosylated Nucleoside Fluorometabolites Related to Nucleocidin in Streptomyces calvus
Xuan Feng, Davide Bello, Phillip T. Lowe, Joshua Clark and David O’Hagan
Chem. Sci., 2019, 10, 9501 – 9505
10.1039/C9SC03374B
286
Fluorine containing cyclopropanes: synthesis of aryl substituted all-cis 1,2,3-trifluorocyclopropanes, a facially polar motif
Zeguo Fang, David B. Cordes, Alexandra M. Z. Slawin and David O’Hagan
Chem. Commun., 2019, 55, 10539 – 10542
10.1039/C9CC05749H
285
An enzymatic Finkelstein reaction: fluorinase catalyses direct halogen exchange
Phillip T. Lowe, Stephen L. Cobb and David O’Hagan
Org. Biomol. Chem., 2019, 17, 7493 – 7496
10.1039/C9OB01625B
284
Fluorine containing substituents: metabolism of the α,α-difluoroethyl thioether motif
Andrea Rodil, Alexandra M. Z. Slawin, Nawaf Al-Maharik, Ren Tomita and David O’Hagan
Beilstein J. Org. Chem.., 2019, 15, 1441-1447
10.1039/C9OB01625B
283
Fluorine in pheromones: Synthesis of fluorinated 12-dodecanolides as Emerald Ash Borer pheromone mimetics
Qingzhi Zhang, Charlotte S. Teschers, Ricardo Callejo, Mingyan Yang, Mingan Wang, Peter J. Silk, Krista Ryall, Lucas E. Roscoe, David B Cordes, Alexandra M. Z. Slawin and David O’Hagan
Tetrahedron., 2019, 7, 2917-2922.
10.1016/j.tet.2019.03.025
282
Enzymatic radiosynthesis of a 18F-Glu-Ureido-Lys-based ligand for the prostate-specific membrane antigen (PSMA)
Phillip T. Lowe, Sergio Dall’Angelo, Ian N. Fleming, Monica Piras, Matteo Zanda and David O’Hagan
Org. Biomol. Chem., 2019, 17, 1480 – 1486
10.1039/C8OB03150A
281
The St Andrews periodic table
David O’Hagan, M Pilar Gil and R A. Aitken,
Chemistry World, 2019, 16 (2), 68-69.
280
Acetyl coenzyme A analogues as rationally designed inhibitors of citrate synthase.
Davide Bello, Maria Grazia Rubanu, Nouchali Bandaranayaka, Jan. P. Götze, Michael Bühl, David O’Hagan
ChemBioChem, 2019, 20, 1174-1182.
10.1002/cbic.201800700