2016 Publications


261
Orgnofluorine chemistry: Difluoromethylene motifs spaced 1,3 to each other imparts facial polarity to cyclohexane ring.

Mathew J. Jones, Ricardo Callejo, Alexandra M. Z. Slawin, Michael Bühl and David O’Hagan

Beilstein J. Org. Chem., 2016, 12, 2823–2827
10.3762/bjoc.12.281


260
Fluorinated liquid crystals: Evaluation of selectively fluorinated facially polarised cyclohexyl motifs for liquid crystal applications.
Nawaf Al-Maharik, Peer Kirsch, Alexandra M. Z. Slawin, David B. Cordes and David O’Hagan

Org. Biol. Chem., 2016, 14, 9974–9980
10.1039/C6OB01986B


259
Last-step enzymatic [18F]-fluorination of cysteine-tethered RGD peptides using modified Barbas linkers.
Qingzhi Zhang, Sergio Dall’Angelo, Ian N. Fleming, Lutz F. Schweiger, Matteo Zanda, David O’Hagan

Chem. Eur. J., 2016, 22, 10998–11004
10.1002/chem.201601361                                                                                


258
Janus Face Aspect of All-cis 1,2,3,4,5,6-Hexafluorocyclohexane Dictates Remarkable Anion and Cation Interactions In the Gas Phase.

Blake E. Ziegler, Michael Lecours,  Rick A. Marta, Joshua Featherstone, Eric Fillion, W. Scott Hopkins, Vincent Steinmetz, Neil S. Keddie, David O’Hagan and Terrance B. McMahon

J. Am. Chem. Soc., 2016, 138, 7460–7463
10.1021/jacs.6b02856

Highlighted in:
ACS C&EN News


257
Fluorinated Musk Fragrances: The CF2 Group as a Conformational Bias Influencing the Odour of Civetone and (R
)-Muscone.
Ricardo Callejo, Michael J. Corr, Mingyan Yang, Mingan A. Wang, David B. Cordes, Alexandra M. Z. Slawin and David O’Hagan

Chem. Eur. J., 2016, 22, 8137–8151
10.1002/chem.201600519


256
Polar alicyclic rings: synthesis and structure of all cis-1,2,3,4-tetrafluorocyclopentane.

Zeguo Fang, Nawaf Al-Maharik, Alexandra M. Z. Slawin, Michael Bühl and David O’Hagan

Chem. Commun., 2016, 52, 5116–6119.
10.1039/C6CC01348A                                          


255
Enzymatic transhalogenation of dendritic RGD peptide constructs with the fluorinase.

Stephen Thompson, Ian N. Fleming and David O’Hagan

Org. Biomol. Chem., 2016, 14, 3120–3129
10.1039/C6OB00239K


254
Accurate Lipophilicity (log P) Measurements Inform on Subtle Stereoelectronic Effects in Fluorine Chemistry.

David O’Hagan and Robert J. Young

Angew. Chem. Int. Ed., 2016, 55, 3858–3860
10.1002/anie.201511055   


253
Common Phenolic Metabolites of Flavonoids, but Not Their Unmetabolized Precursors, Reduce the Secretion of Vascular Cellular Adhesion Molecules by Human Endothelial Cells.

Emily F. Warner, Qingzhi Zhang, K. Saki Rahwm, David O’Hagan, Maria A. O’Connell and Colin D. Kay

J. Nutr., 2016, 146, 3, 465–473
10.3945/jn.115.217943


252
Exploration of a potential difluoromethyl-nucleoside substrate with the fluorinase enzyme.

Stephen Thompson, Stephen A. McMahon, James H. Naismith and David O’Hagan

Bioorg. Chem., 2016, 64, 37–41
10.1016/j.bioorg.2015.11.003


251
Multicomponent reactions of methyl substituted all-cis tetrafluorocyclohexane aldehydes.

Tetiana Bykova, Nawaf Al-Maharik, Alexandra M. Z. Slawin and David O’Hagan

Org. Biomol. Chem., 2016,14, 1117–1123
10.1039/C5OB02334C


250
Inter- and intramolecular CF···C=O interactions on aliphatic and cyclohexane carbonyl derivatives.

Rodrigo A. Cormanich, Roberto Rittner, David O’Hagan and Michael Bühl

J. Comp. Chem., 2016, 37, SI 25–33
10.1002/jcc.23918


249
Fluorine in fragrances: exploring the difluoromethylene (CF2) group as a conformational constraint in macrocyclic musk lactones.

Michael J. Corr, Rodrigo A. Cormanich,  Cortney N. von Hahmann, Michael Bühl, David B. Cordes, Alexandra M. Z. Slawin and David O’Hagan

Org. Biomol. Chem., 2016, 14, 211–219
10.1039/C5OB02023A