The O'Hagan Lab – bio–organic and organofluorine chemistry research

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An enzymatic cascade for high-yield and stereoselective synthesis of 4-fluoro-L-threonine

Thursday November 7, 2024Wednesday October 16, 2024 by Phillip Lowe

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Aryl-fluorocyclopropane β-lactams with activity against Mycobacteroides abscessus and Mycobacterium bovis BCG

Friday October 4, 2024 by Phillip Lowe

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Halogenated Adenine and Adenosine Natural Products in Streptomyces sp. JCM9888

Friday October 4, 2024 by Phillip Lowe

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Synthesis and analysis of (γ,γ’,γ’’-trifluoro)neopentyl (TFNP) aryl ethers as a polar fluoroaliphatic motif.

Friday October 4, 2024 by Phillip Lowe

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Conformational Analysis Explores the Role of Electrostatic Nonclassical CF···HC Hydrogen Bonding Interactions in Selectively Halogenated Cyclohexanes

Friday October 4, 2024 by Phillip Lowe

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Efficient biotransformations in Cunninghamella elegans and Streptomyces sp. JCM9888 of selectively fluorinated benzoic acids to the corresponding benzamides and benzyl alcohols

Thursday October 12, 2023 by Phillip Lowe

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3′-O-β-Glucosyl-4′,5′-didehydro-5′-deoxyadenosine Is a Natural Product of the Nucleocidin Producers Streptomyces virens and Streptomyces calvus

Tuesday September 26, 2023 by Phillip Lowe

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Aryl (β,β′,β″-Trifluoro)-tert-butyl: A Candidate Motif for the Discovery of Bioactives

Friday September 8, 2023 by Phillip Lowe

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Direct syntheses of stereoisomers of 3-fluoro GABA and b-fluoroamine analogues of the calcium receptor (CaR) agonists, cinacalcet, tecalcet, fendilines and NPS R-467

Friday September 8, 2023Tuesday September 5, 2023 by Phillip Lowe

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Congratulations to Dom

Friday September 8, 2023Tuesday August 8, 2023 by Phillip Lowe

Congratulations to Dominic Spurling for winning the poster prized at the 23rd International Symposium on Fluorine Chemistry in Quebec

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