The O'Hagan Lab – bio–organic and organofluorine chemistry research

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Professor David O’Hagan
Research Themes
Group Members
- Postdocs
  - Dr Phillip Lowe
  - Dr Senjuti Halder
- PhD Students
Publications
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Fluorine-Induced Elimination Drives Mechanism-Based Inactivation of Isocitrate Lyase

Wednesday July 22, 2026 by Phillip Lowe

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Incorporation and properties of the tris-fluoromethylated motif into heterocycles, amino acids and analogues of elexacaftor and tezacaftor

Wednesday July 22, 2026Friday July 3, 2026 by Phillip Lowe

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A2A Adenosine Receptor Agonists With Last-Step Enzymatic 18F-Labelling Potential (Fluorinase) for Positron Emission Tomography (PET)

Wednesday February 11, 2026 by Phillip Lowe

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On the Nature of Improper Hydrogen Bonding in RCH2F and RCHF2 Motifs

Thursday November 13, 2025 by Phillip Lowe

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Performance of semiempirical DFT methods for the supramolecular assembly of Janus-face cyclohexanes

Thursday November 13, 2025 by Phillip Lowe

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Bioactivity profiles of progressively ring-fluorinated cyclohexyl motifs in the WKYMVm peptide as formylpeptide FPR2 agonists and in keto-piperazines as anti-trypanosome agents.

Wednesday September 17, 2025 by Phillip Lowe

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Exploring Linear mono-, bis- and tris-Acetylene Containing Agonists of the Human Olfactory Receptor OR1A1

Tuesday June 17, 2025 by Phillip Lowe

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Group away day

Tuesday June 17, 2025 by Phillip Lowe

Recently the group took some time away from the lab and hiked up West Lomond!

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Exploring Fluorinase Substrate Tolerance at C-2 of SAM

Wednesday December 4, 2024Tuesday December 3, 2024 by Phillip Lowe

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Synthesis of Janus All-Cis Tetrafluorocyclohexanes Carrying 1,4-Diether Motifs

Tuesday December 3, 2024 by Phillip Lowe

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