2024 Publications


329
Exploring Linear mono-, bis– and tris-Acetylene Containing Agonists of the Human Olfactory Receptor OR1A1

Weihong Liu, Luca S. Dobson, Chen Zhang, Jiahui Sun, Phillip T. Lowe, Yingjian Liu, Hanyi Zhuang, David O’Hagan

J. Med. Chem., 2025, Article ASAP

doi/10.1021/acs.jmedchem.5c00282


328
Synthesis of Janus All-Cis Tetrafluorocyclohexanes Carrying 1,4-Diether Motifs

Thomas J. Poskin, Bruno A. Piscelli, Aidan P. McKay, David B. Cordes, Yuto Eguchi, Shigeyuki Yamada, Rodrigo A. Cormanich, David O’Hagan

J. Org. Chem., 2025, Article ASAP

doi.org/10.1002/ejoc.202401050


327
Exploring Fluorinase Substrate Tolerance at C-2 of SAM

Phillip T. Lowe, Isabeau Lüddecke and David O’Hagan

ChemBioChem., 2025, e202400861

doi.org/10.1002/cbic.202400861


326
Aryl-Fluorocyclopropane b-Lactams with Activity Against   Mycobacteroides abscessus and Mycobacterium bovis BCG

Dominic E. Spurling, Emily J. Baker, George Kingsley-Moore, Rifahath Mon Neyya Ppadath, Nachiket D. More, Nawaf Al-Maharik, James Harrison, Jonathan A. G. Cox, David O’Hagan

Eur. J. Org. Chem., 202427, in press.

doi.org/10.1002/ejoc.202401050


325
An enzymatic cascade for high-yield and stereoselective synthesis of 4-fluoro-L-threonine.

Alberto De Maria1, Manuel J. Nieto-Domínguez1, Phillip T. Lowe, David O′Hagan, Pablo I. Nikel

Chem. Catalysis, 2024, in press

doi.org/10.1016/j.checat.2024.101148


324
Halogenated Adenine and Adenosine Natural Products in Streptomyces sp. JCM9888

Yawen Chen, Phillip T. Lowe, Hai Deng, David O’Hagan

Eur. J. Org Chem., 2024, 27, e202400578
doi.org/10.1002/ejoc.202400578


323
Synthesis and analysis of (γ,γ’,γ’’-trifluoro)neopentyl (TFNP) aryl ethers as a polar fluoroaliphatic motif.
Atsushi Tarui, Bruno A Piscelli, Nawaf Al-Maharik, Josephine M. Stewart, Patricie Niemcová, David B. Cordes, Aiden P. McKay, Cormac D. Murphy, Rodrigo A. Cormanich and David O’Hagan
Chem. Eur. J., 2024, e202402532
doi.org/10.1002/chem.202402532


322
Conformational analysis explores the role of electrostatic non-classical CF···HC hydrogen bonding interactions in selectively halogenated cyclohexanes.
Mengfan He, Bruno A. Piscelli, Rodrigo A. Cormanich and David O’Hagan
J. Org. Chem., 2024, 89, 4009−4018.
doi.org/10.1021/acs.joc.3c02868.


321
Efficient biotransformations in Cunninghamella elegans and Streptomyces sp. JCM9888 of selectively fluorinated benzoic acids to the corresponding benzamides and benzyl alcohols.
Oluwayinka O. Oke, Yawen Chen, Chukwuemeka Isanbor, Olayinka T. Asekun and David O’Hagan
Biocatal. Biotrans., 2024, 42, 480–484.
doi.org/10.1080/10242422.2023.2267156