Aryl-fluorocyclopropane β-lactams with activity against Mycobacteroides abscessus and Mycobacterium bovis BCG Friday October 4, 2024 by Phillip Lowe Read our paper here
Halogenated Adenine and Adenosine Natural Products in Streptomyces sp. JCM9888 Friday October 4, 2024 by Phillip Lowe Read our paper here
Synthesis and analysis of (γ,γ’,γ’’-trifluoro)neopentyl (TFNP) aryl ethers as a polar fluoroaliphatic motif. Friday October 4, 2024 by Phillip Lowe Read our paper here
Conformational Analysis Explores the Role of Electrostatic Nonclassical CF···HC Hydrogen Bonding Interactions in Selectively Halogenated Cyclohexanes Friday October 4, 2024 by Phillip Lowe Read our paper here
Efficient biotransformations in Cunninghamella elegans and Streptomyces sp. JCM9888 of selectively fluorinated benzoic acids to the corresponding benzamides and benzyl alcohols Thursday October 12, 2023 by Phillip Lowe Read our paper here
3′-O-β-Glucosyl-4′,5′-didehydro-5′-deoxyadenosine Is a Natural Product of the Nucleocidin Producers Streptomyces virens and Streptomyces calvus Tuesday September 26, 2023 by Phillip Lowe Read our paper here
Aryl (β,β′,β″-Trifluoro)-tert-butyl: A Candidate Motif for the Discovery of Bioactives Friday September 8, 2023 by Phillip Lowe Read our paper here
Direct syntheses of stereoisomers of 3-fluoro GABA and b-fluoroamine analogues of the calcium receptor (CaR) agonists, cinacalcet, tecalcet, fendilines and NPS R-467 Friday September 8, 2023Tuesday September 5, 2023 by Phillip Lowe Read our paper here
Congratulations to Dom Friday September 8, 2023Tuesday August 8, 2023 by Phillip Lowe Congratulations to Dominic Spurling for winning the poster prized at the 23rd International Symposium on Fluorine Chemistry in Quebec
Future challenges and opportunities with fluorine in drugs? Friday September 8, 2023Friday July 7, 2023 by Phillip Lowe Read our paper here