Fluorinase Research

The fluorinase is an enzyme that has the unusual abaility to for catalyse the formation of a C-F bond from inorganic fluoride, in water at neutral pH.

We discovered this enzyme in 2002 and we have been working on it ever since. Our recent work is exploring the enzyme as a catalyst to incorporate radioactive fluoride18 fluorine-18 into oto organic molecule as potential clinical imaging agents.